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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25 Days
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report date:
2012

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test)
Deviations:
no
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
1,7-bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione
EC Number:
900-021-3
Molecular formula:
3,5-Heptanedione-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl) :C20 H22O5, 3,5-Heptanedione-1,7 -bis(4-hydroxyphenyl) : C19H20O4, 3,5-Heptanedione-1,7-bis(4-hydroxy-3-methoxyphenyl) : C21H24O6
IUPAC Name:
1,7-bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione
Test material form:
solid: crystalline

Sampling and analysis

Analytical monitoring:
yes
Remarks:
HPLC Method

Test solutions

Vehicle:
yes

Test organisms

Test organisms (species):
Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
72 h

Test conditions

Reference substance (positive control):
yes

Results and discussion

Effect concentrations
Key result
Duration:
72 h
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Remarks on result:
other: Growth Inhibition was found to be greater than 100mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The substance test concentration the mean growth rate of algae was statically not significant.
The EC50 was found to be greater than 100mg per litre.