Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 481-150-8 | CAS number: 500011-86-9
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 13 November 2019 to 19 December 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- Identification: 3-BROMO-1-(3-CHLORO-2-PYRIDINYL)-1HPYRAZOLE-5-CARBOXYLIC ACID
Batch: 628-043-00
CAS number: [500011-86-9]
Purity: 95.3%
Analysis date: 17 October 2019
Expiry date: 17 October 2021
Supplier: ADAMA Makhteshim Ltd.
Appearance: Beige powder
Packaging: White opaque plastic bag
Quantity received: 2 kg
Date of receipt: 12 November 2019
Storage: In darkness at room temperature
Identification number: 19-195 - Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 1.5
- Temp.:
- 25 °C
- Remarks on result:
- other: pH value was not measured, diluent is between pH 2.5 and 3.5 and transferable to complete solution.
- Conclusions:
- Using these guidelines, it was shown that the octanol/water partition coefficient of 3-BROMO-1-(3-CHLORO-2-PYRIDINYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID is equal to 1.5.
- Executive summary:
The objective of this study is to determine the partition coefficient of 3-BROMO-1-(3-CHLORO-2-PYRIDINYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID following the Regulation (EC) No.1907/2006 - and Council regulation (EC) No. 2016/266 - EC A.24. method (2016) and using the HPLC test method OECD Guideline No. 117 (2004).
Using these guidelines, it was shown that the octanol/water partition coefficient of 3-BROMO-1-(3-CHLORO-2-PYRIDINYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID is equal to 1.5.
Reference
Description of key information
The objective of this study is to determine the partition coefficient of 3-BROMO-1-(3-CHLORO-2-PYRIDINYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID following the Regulation (EC) No.1907/2006 - and Council regulation (EC) No. 2016/266 - EC A.24. method (2016) and using the HPLC test method OECD Guideline No. 117 (2004).
Using these guidelines, it was shown that the octanol/water partition coefficient of 3-BROMO-1-(3-CHLORO-2-PYRIDINYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID is equal to 1.5.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 1.5
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
