Registration Dossier

Diss Factsheets

Toxicological information

Acute Toxicity: oral

Currently viewing:

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
publication
Title:
Acute Toxicity Data
Year:
1941
Bibliographic source:
Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. 23,259,1941

Materials and methods

Test guideline
Qualifier:
no guideline available
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2-benzyloxyethanol
EC Number:
210-719-3
EC Name:
2-benzyloxyethanol
Cas Number:
622-08-2
Molecular formula:
C9H12O2
IUPAC Name:
2-(benzyloxy)ethanol
Test material form:
liquid

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Doses:
Not Specified
No. of animals per sex per dose:
Not Specified
Control animals:
not specified
Details on study design:
Not Specified
Statistics:
Not Specified

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
ca. 1 190 mg/kg bw
Clinical signs:
BEHAVIORAL: General anesthetic

Applicant's summary and conclusion

Interpretation of results:
Category 4 based on GHS criteria
Conclusions:
Acute Oral LD50 value of 1190 mg/kg bw was determined in a study with limited reliability. In this regard, No details on the study are available. However, The identified value allowed to allocate the substance in the category 4 following GHS Criteria (300 mg/kg bw