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Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
4 February 2020 - 5 February 2020
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2020
Report date:
2020

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Reference substance name:
Extract from the seeds of Trigonella foenum-graecum (Fabaceae) obtained by extraction with polar solvents
EC Number:
950-727-0
Molecular formula:
Fenugreek extract
IUPAC Name:
Extract from the seeds of Trigonella foenum-graecum (Fabaceae) obtained by extraction with polar solvents
Specific details on test material used for the study:
Identification/Synonym FENUGREEK EXTRACT
Substance type UVCB substance
EC No. 950-727-0
Storage conditions room temperature, protected from light

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
-2.8 - 1.8
Temp.:
40 °C
pH:
6.9

Applicant's summary and conclusion

Conclusions:
The partition coeffiecient of the substance has been determined to be between Log Pow -2.8 to 1.8