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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification

Data source

Reference
Title:
ECOSAR (US EPA)
Year:
2017
Bibliographic source:
ECOSAR (US EPA) Version 2.0

Materials and methods

Principles of method if other than guideline:
- Software tool(s) used including version: ECOSAR (US EPA)
- Model(s) used: ECOSAR (US EPA) Version 2.0
- Model description: see field 'Attached justification'
GLP compliance:
no

Test material

1
Chemical structure
Reference substance name:
(S)-3-(tert-butylamino)propane-1,2-diol
EC Number:
250-125-1
EC Name:
(S)-3-(tert-butylamino)propane-1,2-diol
Cas Number:
30315-46-9
Molecular formula:
C7H17NO2
IUPAC Name:
(2S)-3-(tert-butylamino)propane-1,2-diol
Test material form:
solid: particulate/powder

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
99.65 mg/L
Nominal / measured:
estimated
Remarks on result:
other: QSAR prediction

Applicant's summary and conclusion

Conclusions:
(2S)-3-(tert-butylamino)propane-1,2-diol is a organic chemical that is likely to be within the domain of ECOSAR domain.
Aliphatic Amines SAR: Daphnid 48-hr LC50 = 99.65 mg/L

The predictions do not indicate extreme or acute toxicities relevant for classification and labelling. The assessment indicates that the prediction is suitable for the regulatory conclusion.

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