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Environmental fate & pathways

Biodegradation in water: screening tests

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In order to assess the biodegradation of Rosamusk, a screening test was performed according to OECD TG 301D (Closed Bottle test) and under GLP conditions (Klimisch 1). In this study, river water was exposed to 2 mg/L of the substance for 60 days. Rosamusk was not toxic to inoculum because it did not cause a reduction in the endogenous respiration. Furthermore, the validity criteria of the test were met. Rosamusk was biodegraded by 33% on day 28 in the standard Closed Bottle screening test, not being readily biodegradable. In the prolonged Closed Bottle test, the test item was biodegraded by 66% on day 60 (enhanced biodegradability testing). A biodegradation percentage of >60 within a 60 -day time period allows classification of Rosamusk as not persistent.

Key value for chemical safety assessment

Biodegradation in water:
not biodegradable

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