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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

In order to assess the biodegradation of the test substance, a screening test was performed according to OECD TG 301D (Closed Bottle test) and under GLP conditions. In this study river water was exposed to 2.0 mg/L of the test substance for 28 days. Inhibition of the endogenous respiration of the inoculum by the test substance at day 7 was not detected. The test is valid as shown by an endogenous respiration of 1.45 mg/L and by the total mineralization of the reference compound, sodium acetate. Sodium acetate was degraded by 89% of its theoretical oxygen demand after 14 days. The oxygen concentrations were >0.5 mg/L in all bottles during the test period. The test substance was biodegraded for 80% at day 28. Over 60% biodegradation was achieved in a period of approximately 13 days immediately following the attainment of 10% biodegradation thereby fulfilling the time window criterion for ready biodegradable substances in a Closed Bottle Test. The test item should therefore be classified as readily biodegradable.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information