1H-Pyrazole-4-carbonyl chloride, 3-(difluoromethyl)-1-methyl-

Toxicity to microorganisms

Administrative data

Endpoint:

activated sludge respiration inhibition testing

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2009

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method C.11 (Biodegradation: Activated Sludge Respiration Inhibition Test)

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid

EC Number:

700-093-4

Cas Number:

176969-34-9

Molecular formula:

C6H6F2N2O2

IUPAC Name:

3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid

Constituent 2

Reference substance name:

700-93-4

IUPAC Name:

700-93-4

Sampling and analysis

Analytical monitoring:

no

Test organisms

Test organisms (species):

activated sludge of a predominantly domestic sewage

Study design

Test type:

static

Water media type:

freshwater

Limit test:

yes

Total exposure duration:

3 h

Results and discussion

Effect concentrations

Duration:

3 h

Dose descriptor:

EC50

Effect conc.:

> 1 000 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

inhibition of total respiration

Remarks:

respiration rate

Applicant's summary and conclusion

Validity criteria fulfilled:

yes