Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

The test material was non-mutagenic in bacteria and did not induce chromosome damage in human peripheral blood lymphocytes. Those data were supported by a structurally similar substance, which failed to cause gene mutation in mouse lymphoma cells. 


Short description of key information:
Negative for mutagenic effect on bacteria (OECD 471).

Negative for induction of structural and numerical chromosome aberrations (OECD 473).

Behaviour of a close chemical analogue strongly predicts the substance will be negative for gene mutation in mouse lymphoma cells (OECD 476).

Endpoint Conclusion: No adverse effect observed (negative)

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Genetic toxicity in vivo

Description of key information

An in vivo micronucleus study was conducted in the read-across analogue substance EC No 931-276-9, for notification in another region. The study can be used for the registration substance. The results of the test were negative, and support the in vitro conclusions. 


Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Additional information

Justification for classification or non-classification

The test substance does not meet criteria for classification under the terms of Directive 67/548/EEC or GHS as reflected by Regulation (EC) 1272/2008.