Registration Dossier
Registration Dossier
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EC number: 422-930-1 | CAS number: 780759-89-9 JAUNE TZ 4210
Endpoint summary
Administrative data
Link to relevant study record(s)
- Endpoint:
- basic toxicokinetics, other
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Reference
Description of key information
FAT40549 is considered having a low potential for absorption (oral 20%, dermal 10% and inhalation 10%) and also a low potential, if any, for bioaccumulation.
Key value for chemical safety assessment
- Bioaccumulation potential:
- low bioaccumulation potential
- Absorption rate - oral (%):
- 20
- Absorption rate - dermal (%):
- 10
- Absorption rate - inhalation (%):
- 10
Additional information
Due to the physico-chemical properties (i.e., high molecular weight, high water solubility, particle size, low LogPow) FAT40549/A is expected to be absorbed in human body via different routes - oral (assumed 20%), dermal (assumed 10%) and inhalation (assumed 10%). Following absorption, FAT40549/A is anticipated to be distributed in blood, liver and kidney. Excretion is expected via urine, bile or feces, and as a conclusion FAT 40549/A has a poor accumulation potential in the human body.
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