Registration Dossier

Diss Factsheets

Administrative data

Link to relevant study record(s)

basic toxicokinetics, other
Data waiving:
other justification
Justification for data waiving:

Description of key information

FAT40549 is considered having a low potential for absorption (oral 20%, dermal 10% and inhalation 10%) and also a low potential, if any, for bioaccumulation.

Key value for chemical safety assessment

Bioaccumulation potential:
low bioaccumulation potential
Absorption rate - oral (%):
Absorption rate - dermal (%):
Absorption rate - inhalation (%):

Additional information

Due to the physico-chemical properties (i.e., high molecular weight, high water solubility, particle size, low LogPow) FAT40549/A is expected to be absorbed in human body via different routes - oral (assumed 20%), dermal (assumed 10%) and inhalation (assumed 10%). Following absorption, FAT40549/A is anticipated to be distributed in blood, liver and kidney. Excretion is expected via urine, bile or feces, and as a conclusion FAT 40549/A has a poor accumulation potential in the human body.