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EC number: 701-316-8 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: OSPAR Commission 2006 Part B. Protocol for a fish acute toxicity test
- Version / remarks:
- consistent with OECD 203 guideline as adapted by OSPAR
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Version / remarks:
- consistent with OECD 203 guideline as adapted by OSPAR Commission 2006 Part B for marine testing of offshore chemicals
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Reported as: Acidgen FG3
- Analytical monitoring:
- no
- Vehicle:
- no
- Details on test solutions:
- Natural local seawater is pumped to holding tanks from Scapa Flow, Orkney. The treatment process was: sand filtered to remove particulate, filtered to 1 µm, heated to 16 ºC, UV treated, degassed and held at a quantity of 3000 to 5000 litres. The water is constantly pumped through the system and trickle replenished as the water is used.
- Test organisms (species):
- Cyprinodon variegatus
- Details on test organisms:
- TEST ORGANISM
- Common name: Sheepshead minnow
- Source: reared and maintained at Opus Maxim Ltd.
- Length at study initiation; 1.5-2.5 cm - Test type:
- semi-static
- Water media type:
- saltwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
- Test temperature:
- 20±2 ºC
- Dissolved oxygen:
- 97.1-101.8%
- Salinity:
- 33.0-33.3 ‰
- Nominal and measured concentrations:
- Limit test: 74.31 mg/L
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 5 litre capacity glass beakers containing 3 litres of test media
- Aeration: Gentle aeration was supplied to all tanks
- Renewal rate of test solution: with replacement of media after 48h
- No. of organisms per vessel: 10
- No. of vessels per concentration: 1
- No. of vessels per control: 1 - Reference substance (positive control):
- no
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 74.31 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- No mortality was reported
- Validity criteria fulfilled:
- yes
- Conclusions:
- Acidgen FG3 exhibited no effect at 74.31 mg/L after 96h (directly via seawater) to the marine fish Cyprinodon variegatus in the water phase.
- Executive summary:
A 96h limit test in marine water for the test material using Cyprinodon variegatus was conducted according to OSPAR Commission 2006 Part B Protocol for a fish acute toxicity test which is adapted from the OCED TG 203 for the marine environment. The test concentration is based on the LC/EC50 of the test material between most the sensitive species Skeletonema costatum and Acartia tonsa. Testing has indicated that the algal species was the more sensitive from allied studies.
Ten fish were exposed to 74.3 mg/L for 96 hours with replacement of media after 48h. No mortality was reported in either the test concentration or the control vessels. All validity criterion were met and the test substance exhibited no effect at 74.31mg/L after 96h (directly via seawater) to the marine fish Cyprinodon variegatus in the water phase.
Reference
Description of key information
A 96h limit test in marine water for the test material using Cyprinodon variegatus was conducted according to OSPAR Commission 2006 Part B Protocol for a fish acute toxicity test which is adapted from the OCED TG 203 for the marine environment. The test concentration is based on the LC/EC50 of the test material between most the sensitive species Skeletonema costatum and Acartia tonsa. Testing has indicated that the algal species was the more sensitive from allied studies.
Ten fish were exposed to 74.3 mg/L for 96 hours with replacement of media after 48h. No mortality was reported in either the test concentration or the control vessels. All validity criterion were met and the test substance exhibited no effect at 74.31mg/L after 96h (directly via seawater) to the marine fish Cyprinodon variegatus in the water phase.
Key value for chemical safety assessment
Marine water fish
Marine water fish
- Effect concentration:
- 74.3 mg/L
Additional information
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