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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
bulk density
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Version / remarks:
2 October 2012
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
air comparison pycnometer (for solids)

Test material

Constituent 1
Chemical structure
Reference substance name:
4-[3-(3,5-dichloro-4-fluorophenyl)-4,4,4-trifluorobut-2-enoyl]-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide
Molecular formula:
C23H18Cl2F4N2O4
IUPAC Name:
4-[3-(3,5-dichloro-4-fluorophenyl)-4,4,4-trifluorobut-2-enoyl]-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide
Test material form:
solid
Details on test material:
Off-white

Results and discussion

Density
Key result
Type:
bulk density
Density:
1.46 g/cm³
Temp.:
20 °C

Any other information on results incl. tables

Results of calibration: The pressure readings and the calculated volume for the reference and sample cells were done as described. As the reference cell volume and sample cell volume were within the defined tolerance (90.953 ± 1.0 cm3 and 149.225 ± 1.0 cm3 for the reference and sample cell volumes respectively) the gas comparison pycnometer was therefore considered acceptable for use.

Applicant's summary and conclusion

Conclusions:
The density of the test substance was determined to be 1.46 g/cm3 at 20 ± 0.5 °C.
Executive summary:

The density of the test substance was determined under GLP to OECD TG 109 using the gas comparison pycnometer method. This methods allows determination of the true volume of solid samples and through the known mass of the sample taken, also the density of the sample. The instrument, which consists of a reference cell and a sample cell that are interlinked can be pressurised with helium, which is an inert gas demonstrating ideal gas behaviour. The volumes of these two cells are confirmed prior to the test sample analysis through the use of a stainless steel calibration sphere of defined volume. The analysis of the volume of a previously weighed amount of test sample is then performed by determining the pressure drop for the pressurised reference cell when the additional volume of the sample cell containing the test material is added. Two separate experiments were conducted, using aliquots of 29.4148 and 30.9069 g test substance. Triplicate pressure readings were taken after purging and pressurising the reference cell and then switching to the sample cell. The volumes obtained for the reference cell and the sample cell determined during calibration were within the defined tolerance and the instrument was considered acceptable for use. The density of the test substance was determined to be 1.46 g/cm3 at 20.0 ± 0.5 °C.