Registration Dossier
Registration Dossier
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EC number: 457-670-6 | CAS number: 157859-20-6
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 12 February 2004
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of relevant results.
Cross-reference
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 004
- Report date:
- 2004
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- (Date of inspection: 02 December 2002 Date of signature: 13 February 2003)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
- Details on test material:
- - Name of test material (as cited in study report): TIPX
- Substance type: Colourless liquid.
- Physical state: Liquid.
- Lot/batch No.: 042028.
- Storage condition of test material: Approximately 4ºC in the dark.
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- > 6.2
- Temp.:
- 25 °C
- Details on results:
- log Pow of > 6.2 at 25°C.
Any other information on results incl. tables
log Pow of > 6.2 at 25°C.
Applicant's summary and conclusion
- Conclusions:
- The partition coefficient of the test material has been determined to be >1.59 x 106, log10 Pow >6.20.
- Executive summary:
Partition Coefficient has been determined to be >1.59 x 106, log10Pow, >6.20 using the HPLC method, Method A8 of Commission Directive 92/69/EEC.
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