Registration Dossier
Registration Dossier
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EC number: 203-996-7 | CAS number: 112-67-4
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Parent compound palmitoyl chloride: In contact with water the substance hydrolyses rapidly (t1/2 < 5 min).
Hydrolysis product palmitic acid: Palmitic acid is readily biodegradable.
Key value for chemical safety assessment
Additional information
Parent compound palmitoyl chloride (CAS 112-67-4):
The hydrolysis of the substance was studied according to OECD 111 at pH 4, 7, and 9 at 10, 20, and 50°C (BASF SE, 2020; study no. 20L00159). The hydrolytic half-life was determined to be t1/2 < 5 min at all pH values and temperatures. Palmitic acid and hydrochloric acid were determined as transformation products.
Hydrolysis products:
According to Regulation (EC) No 1907/2006, Annex VIII, Section 9.2.2.1, Column 2, the study on hydrolysis as a function of pH does not need to be conducted if the substance is readily biodegradable. Palmitoyl chloride (CAS 112-67-4) hydrolyses rapidly and forms palmitic acid (CAS 57-10-3) and hydrochloric acid (HCl, CAS 7647-01-0). Palmitic acid is readily biodegradable (see IUCLID Ch. 5.2.1), while HCl is inorganic. Therefore, a study on the hydrolysis is not provided.
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