Registration Dossier
Registration Dossier
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EC number: 271-587-0 | CAS number: 68585-78-4
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 976
- Report date:
- 1976
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EPA OPP 81-1 (Acute Oral Toxicity)
- Deviations:
- no
- GLP compliance:
- yes
- Test type:
- acute toxic class method
- Limit test:
- no
Test material
- Reference substance name:
- Trihydrogen tris[P,P-dioctyl diphosphato(2-)-O'',O''''](propan-2-olato)titanate(3-), branched and linear
- EC Number:
- 271-587-0
- EC Name:
- Trihydrogen tris[P,P-dioctyl diphosphato(2-)-O'',O''''](propan-2-olato)titanate(3-), branched and linear
- Cas Number:
- 68585-78-4
- Molecular formula:
- Not applicable
- IUPAC Name:
- Reaction product of titanium tetraisopropanolate and Dioctyl Dihydrogen Diphosphate
- Test material form:
- liquid: viscous
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- unchanged (no vehicle)
- Details on oral exposure:
- animals wre observed daily for 14 days after administration of test substance.
- No. of animals per sex per dose:
- 5
- Control animals:
- no
Results and discussion
Effect levels
- Key result
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- No mortality observed.
- Clinical signs:
- other: No specific findings.
- Gross pathology:
- No specific findings.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- Rats received up to 5 ml/kg bw by oral gavage and no mortality observed. The LD50 was calculated to be > 5000 mg/kg bw. GHS criteria not met.
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