Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

First-aid measures

- General advice:

Do not leave the victim unattended.

- Following inhalation:

Move to fresh air.

If unconscious, place in recovery position and seek medical advice.

If symptoms persist, call a physician.

- Following skin contact:

If on skin, rinse well with water.

- Following eye contact:

Immediately flush eye(s) with plenty of water.

Remove contact lenses.

Protect unharmed eye.

Keep eye wide open while rinsing.

If eye irritation persists, consult a specialist.

- Following ingestion:

Keep respiratory tract clear.

Do not give milk or alcoholic beverages.

Never give anything by mouth to an unconscious person.

If symptoms persist, call a physician.

Rinse mouth with water.

- Most important symptoms and effects:None known.

Fire-fighting measures

Suitable extinguishing media - water spray jet, dry powder, foam, carbon dioxide

- adapt extinguishing media to surrounding fire conditions

Specific hazards - formation of toxic and corrosive combustion gases (hydrogen

chloride, hydrogen fluoride, nitrogen oxides) possible

- substance is hazardous for water: contain fire-fighting wastewater

Protection of fire-fighters - precipitate gases/vapours/mists with water spray

Special method of fire-fighting - if possible precipitate fire gases with a water jet- Suitable extinguishing media:

Use extinguishing measures that are appropriate to local cir-cumstances and the surrounding environment.

- Unsuitable extinguishing media:

High volume water jet

- Special hazards arising from the substance or mixture:

Specific hazards during fire-fighting :

Do not allow run-off from fire fighting to enter drains or water courses.

Hazardous combustion products :

In case of fire hazardous decomposition products may be produced such as:

Carbon monoxide

Nitrogen oxides (NOx)

Gaseous hydrogen chloride (HCl).

Hydrogen fluoride

- Advice for fire fighter:

Special protective equipment for firefighters:

Wear self-contained breathing apparatus for firefighting if necessary.

Further information:

Collect contaminated fire extinguishing water separately. This must not be discharged into drains.

Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local regulations.

Accidental release measures

Environmental protection -

-Prevent product from entering drains.

-Prevent further leakage or spillage if safe to do so.

-If the product contaminates rivers and lakes or drains inform respective authorities.

Methods for cleaning up - collect spilled material (avoid dust formation) and hand over to

waste removal in sealed containers

Handling and storage

Handling

Technical measures - processing in closed systems, if possible superposed by inert gas

(e.g. nitrogen)

- low probability of ignition: ground plant, avoid effective ignition

sources

- avoid dust formation; high dust explosion hazard

Storage

Storage conditions - room temperature

- protected from light and humidity- Precautions for safe handling:

Advice on safe handling:

Smoking, eating and drinking should be prohibited in the ap-plication area.

Dispose of rinse water in accordance with local and national regulations.

Advice on protection against fire and explosion:

Provide appropriate exhaust ventilation at places where dust is formed.

Hygiene measures:

When using do not eat or drink. When using do not smoke. Wash hands before breaks and at the end of workday.

- Conditions for safe storage, including any incompatibilities:Requirements for storage areas and containers:

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully re-sealed and kept upright to prevent leakage. Electrical installa-tions / working materials must comply with the technological safety standards.

Further information on stor-age conditions:

See label, package insert or internal guidelines

Storage class (TRGS 510):

13, Non Combustible Solids

Storage temperature:

Store at room temperature. Protected from heat and light

Further information on storage stability:

No decomposition if stored and applied as directed.

Packaging material:

Suitable material: Stainless steel, Polyethylene bag in metal drum

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:
3077
Shipping information
Proper shipping name and description:
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
Chemical name:
(1-Propanesulfonamide, N-[3-[[5-(4-chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-)
Class or division:
Class 9: Miscellaneous dangerous substances and articles, including environmentally hazardous substances
Labels:
not classified by transport regulations
SpecialProvisionsopen allclose all

Inland waterway transport (UN RTDG/ADN(R))

UN number:
3077
Shippingopen allclose all
Class or division:
Class 9: Miscellaneous dangerous substances and articles, including environmentally hazardous substances
Packing group:
Packing group III: Substances presenting low danger
Labels:
9
Remarksopen allclose all

Marine transport (UN RTDG/IMDG)

UN number:
3077
Shipping information
Proper shipping name and description:
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
Chemical name:
(1-Propanesulfonamide, N-[3-[[5-(4-chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-)
Class or division:
Class 9: Miscellaneous dangerous substances and articles, including environmentally hazardous substances
Packing group:
Packing group III: Substances presenting low danger
EmS code:
F-A
S-F
Labels:
9
Marine pollutant
Remarksopen allclose all

Air transport (UN RTDG/ICAO/IATA)

UN number:
3077
Shipping information
Proper shipping name and description:
Environmentally hazardous substance, solid, n.o.s.
Chemical name:
(1-Propanesulfonamide, N-[3-[[5-(4-chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-)
Class or division:
Class 9: Miscellaneous dangerous substances and articles, including environmentally hazardous substances
Packing group:
Packing group III: Substances presenting low danger
Labels:
9
Special provisions / remarks
Remarks:
Packing instruction (cargo aircraft)(passenger aircraft): 956
Packing instruction (LQ): Y956
SpecialProvisionsopen allclose all

Exposure controls / personal protection

OEL 0,01 mg/m3

Engineering Measures

- Handling

Technical measures - processing in closed systems, if possible superposed by inert gas

(e.g. nitrogen)

- low probability of ignition: ground plant, avoid effective ignition

sources

- avoid dust formation; high dust explosion hazard

Personal protective equipment

Respiratory protection - in case of open handling or accidental release:

particle mask or respirator with independent air supply

Hand protection - protective gloves (eg made of neoprene, nitrile or butyl rubber) The selected protective gloves have to satisfy the specifica-tions of Regulation (EU) 2016/425 and the standard EN 374 derived from it. This recommendation is only valid for the product mentioned in the safety data sheet and provided by us and for the application specified by us. Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. Also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion, and the contact time. The suitability for a specific workplace should be discussed with the producers of the protective gloves.

Eye protection - Eye wash bottle with pure water

Tightly fitting safety goggles

Stability and reactivity

Conditions to avoid

- warming

- light1. Reactivity

No dangerous reaction known under conditions of normal use.

2. Chemical stability

Stable under normal conditions.

3. Possibility of hazardous reactions

Hazardous reactions:

No data available

No decomposition if stored and applied as directed.

4. Conditions to avoid

Do not expose to temperatures above: 150 °C

5. Incompatible materials

No data available

6. Hazardous decomposition products

No data available

Disposal considerations

Waste treatment methods

Product:

The product should not be allowed to enter drains, water courses or the soil.

Do not contaminate ponds, waterways or ditches with chemical or used container.

Send to a licensed waste management company.

Contaminated packaging:

Empty remaining contents.

Dispose of as unused product.

Empty containers should be taken to an approved waste handling site for recycling or disposal.

Do not re-use empty containers.