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Description of key information

Key value for chemical safety assessment

Additional information

The registered substance was tested in a single dose of 2000 mg/kg bw in an acute oral toxicity study in female Wistar rats following OECD TG 420. There were no deaths during the study. As clinical signs hunched posture, stained faeces (dark red), decreased activity, fur stained by test item, piloerection, partially closed eyes, abdominal tension, secretion of Haderian glands, and nervousness were noted in the first two days after dosing. The animal showed expected gains in body weight over the observation period. The acute median lethal oral dose (LD50) to rats of Macrolex Fluoreszenzrot 4B was demonstrated in this study to be greater than 2000 mg/kg body weight.

Justification for classification or non-classification

According to CLP classification criteria (Regulation (EC) No 1272/2008) a classification is not justified.