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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2021-06-21
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
Version / remarks:
1981
Qualifier:
according to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
Version / remarks:
European Commission Regulation (EC) No. 440/2008
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Version / remarks:
2009
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of particle tested:
agglomerate
Type of distribution:
volumetric distribution
Key result
Percentile:
D10
Mean:
2.2 µm
Remarks on result:
other: St. dev. not determined
Key result
Percentile:
D50
Mean:
12.6 µm
Remarks on result:
other: st. dev. not determined.
Key result
Percentile:
D90
Mean:
115 µm
Remarks on result:
other: st. dev. not determined.

The test item consisted of irregularly shaped opaque particles. The particles were introduced to the analyser beam by the dry powder feeder by direct spraying


through the measurement area. The powder was loosened by an integrated vibrator. The particles


were dispersed and fed to the optical system by pressurized dry air (1.5 bar). After passing the


analyser beam the sample was collected in a vacuum cleaner.


After adjusting the laser, measuring the background and adjusting the correct particle concentration (obscuration) the measurement was started. The control software automatically performed three measurements. The average of these three measurements was given as result. Two test series of three measurements each were performed. The measurement time was 12 s. Median values were calculated from unrounded values.


 


The median particle size L50 (D (v, 0.5): 50 % of particle volume or particle mass with lower particle diameter) deduced from these distributions were:


1st test series: L50 = 12.65 μm


2nd test series: L50 = 12.54 μm


The average of the median particle size L50 was: L50 = 12.6 μm


 


The particle size L10 (D (v, 0.1 ): 10 % of particle volume or particle mass with lower particle diameter) deduced from these distributions were:


1st test series: L10 = 2.22 μm


2nd test series: L10 = 2.19 μm


The average of the particle size L10 was: L10 = 2.2 μm


 


The particle size L90 (D (v, 0.9): 90 % of particle volume or particle mass with lower particle diameter) deduced from these distributions were:


1st test series: L90 = 118.3 μm


2nd test series: L90 = 111.3 μm


The average of the particle size L90 was: L90 = 115 μm


 


The maximum was observed at approximately 90 μm. Additionally shoulders were observed at


approximately 1 μm and approximately 15 μm.


 


 


 

Conclusions:
The median particle size L50 of the test item deduced from the particle size distributions was 12.6 μm.
Executive summary:

The determination of the particle size distribution by laser diffraction of the test item was performed according to the OECD Guideline 110 by laser diffraction. The median particle size L50 of the test item deduced from the particle size distributions was 12.6 μm.

Description of key information

The median particle size L50 of the test item deduced from the particle size distributions was 12.6 µm.

Additional information

The determination of the particle size distribution by laser diffraction of the test item was performed according to the OECD Guideline 110. The median particle size L50 of the test item deduced from the particle size distributions was 12.6 μm.

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