Registration Dossier
Registration Dossier
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EC number: 429-130-1 | CAS number: 2820-37-3
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
- Objective of study:
- absorption
- excretion
- toxicokinetics
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 417 (Toxicokinetics)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method B.36 (Toxicokinetics)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 870.7485 (Metabolism and Pharmacokinetics)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other:
- Deviations:
- no
Test material
Constituent 1
- Radiolabelling:
- yes
Test animals
- Species:
- mouse
- Strain:
- C57BL
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: gavage
Results and discussion
Main ADME resultsopen allclose all
- Type:
- absorption
- Type:
- distribution
- Type:
- excretion
- Type:
- other:
Toxicokinetic / pharmacokinetic studies
Toxicokinetic parametersopen allclose all
- Key result
- Test no.:
- #1
- Toxicokinetic parameters:
- Cmax:
- Key result
- Test no.:
- #2
- Toxicokinetic parameters:
- Cmax:
- Key result
- Test no.:
- #3
- Toxicokinetic parameters:
- Cmax:
- Key result
- Test no.:
- #4
- Toxicokinetic parameters:
- Cmax:
Metabolite characterisation studies
- Metabolites identified:
- not measured
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
