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Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2019-02-14 to 2019-02-20
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
The study was conducted according to an internationally recognised method, and under GLP. Test substance is adequately characterised. Therefore full validation applies.
Reason / purpose for cross-reference:
reference to same study
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
2008
Deviations:
no
Principles of method if other than guideline:
not applicable
GLP compliance:
yes (incl. QA statement)
Remarks:
Date of inspection: October 11th - October 12th, 2016 / Date of signature: February 28th, 2017
Type of method:
differential scanning calorimetry
Key result
Melting / freezing pt.:
>= -60 - <= -20 °C
Atm. press.:
1 025 hPa
Decomposition:
no

Results of the DSC-measurements:

Sample weight (mg)

Phase

Range of effect (°C)

Pressure (hPa)

8.78

Cooling

-30 to -35

1025.0

Heating

-60 to -20

280 to 400

10.93

Cooling

-30 to -35

1025.0

Heating

-60 to -20

280 to 410

During the cooling phase, an exothermal effect at the temperature of approx. -30 °C was observed, which can be assigned to the freezing of the test item.

During the heating phase a distinct endothermic effect was observed in the temperature range of -60 to -20 °C, which can be assigned to the melting of the test item.

The test item showed a second endothermic signal in the temperature range of approx.280 – 410 °C. No further thermal effects were observed up to the maximum test temperature of 500 °C.

Conclusions:
The determination of the melting point of the test item was performed according to OECD 102 and EU A1 guidelines, by Differential Scanning Calorimetry.
The test item showed a melting range, no melting point. As the test item is an UVCB substance this is considered as normal.
A melting range of -60°C to -20°C was found at 1025 hPa.
Executive summary:

The determination of the melting point of the test item was performed according to OECD 102 and EU A1 guidelines, by Differential Scanning Calorimetry.

The test item showed a melting range, no melting point. As the test item is an UVCB substance this is considered as normal.

A melting range of -60°C to -20°C was found at 1025 hPa.

Description of key information

A melting range of -60°C to -20°C was found at 1025 hPa by Differential Scanning Calorimetry.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
-20 °C

Additional information

A fully reliable experimental study, conducted according to OECD 102/ EU A1 guideline is available.

It is considered as a key study, and the result is retained as key data.