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Description of key information

In silico prediction by Derek Nexus for skin sensitization (August 2021): negative

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Additional information:

An in silico assessment for skin sensitization of DFPP-malat was carried out in August 2021 with the following tools:

Derek Nexus: 6.1.0, Nexus: 2.3.0

Selected Knowledge Base: Derek KB 2020 1.0


DEREK prediction: non sensitizer 

no misclassified or unclassified features



The parameters that have influenced your prediction are: substructures in the input structure, which have the potential to cause skin sensitisation; your selected species, which is mammal.

The query structure does not match any structural alerts or examples for skin sensitisation in Derek. Additionally, the query structure does not contain any unclassified or misclassified features and is consequently predicted to be a non-sensitiser.

Justification for classification or non-classification