Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2019-07-08 to 2019-08-12
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 1995
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- 1.394 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 7 000 mg/L
- Temp.:
- 20 °C
- pH:
- 6.348
- Remarks on result:
- other: Mean value
- Water solubility:
- 1.39 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 7 000 mg/L
- Incubation duration:
- 24 h
- Temp.:
- 20 °C
- pH:
- 6.546
- Water solubility:
- 1.392 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 7 000 mg/L
- Incubation duration:
- 48 h
- Temp.:
- 20 °C
- pH:
- 6.291
- Water solubility:
- 1.399 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 7 000 mg/L
- Incubation duration:
- 72 h
- Temp.:
- 20 °C
- pH:
- 6.205
- Conclusions:
- The water solubility of the test item was determined to be 1.394 g/L at 20°C and pH 6.348.
- Executive summary:
The water solubility of test item was determined according to OECD guideline 105 and GLP. The test was performed using the flask method at 20°C with a pre-incubation at 30°C. The concentration was analyzed via the HPLC-DAD method. The water solubility of the test item was determined to be 1.394 g/L at 20°C and pH 6.348.
Reference
Description of key information
A study of the water solubility of test item was determined according to OECD guideline 105 and GLP. The test was performed using the flask method at 20°C with a pre-incubation at 30°C. The concentration was analyzed via the HPLC-DAD method. The water solubility of the test item was determined to be 1.394 g/L at 20°C and pH 6.348.
Key value for chemical safety assessment
- Water solubility:
- 1.394 g/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
