4-chlorobenzoic acid

Boiling point

Administrative data

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

03.08.2021

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2021

Report date:

2021

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

not specified

Test guideline 2

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Version / remarks:

1995

Deviations:

not specified

GLP compliance:

no

Type of method:

differential scanning calorimetry

Test material

Test material information

Constituent 1

Reference substance name:

4-chlorobenzoic acid

EC Number:

200-805-9

EC Name:

4-chlorobenzoic acid

Cas Number:

74-11-3

Molecular formula:

C7H5ClO2

IUPAC Name:

4-chlorobenzoic acid

Test material form:

solid: particulate/powder

Details on test material:

white to yellowish crytalline powder

Results and discussion

Boiling point

Key result

Boiling pt.:

277.8 °C

Atm. press.:

1 013 hPa

Decomposition:

no

Any other information on results incl. tables

In the temperature range of 230 – 260 °C, an endothermic effect was observed. Between 260 – 300 °C a second endothermic effect could be detected. No further thermal effects were observed up to the test end temperature of 500 °C.

Table 1:    Results of the DSC-measurements

Measurement No.	Sample weight / mg	Onset of Effect / °C	Range of effect / °C	Weight loss / mg	Atmospheric pressure / hPa	Remark
PN20973	11.07	239.12 277.83	230 – 260 (endo) 260 – 300 (endo)	11.07	1012.2	Figure 1
PN20974	11.17	239.36 277.69	230 – 260 (endo) 260 – 300 (endo)	11.17	1012.1	Figure 2

During the heating phase a distinct endothermic effect was observed in the temperature range of 230 – 260 °C, which can be assigned to the melting of the test item.

As the onset temperatures in both tests do not deviate by more than 0.5 K from their mean value of 239.24 °C, this temperature can be used as melting point. The test item has a melting point of 239.2 °C.

The test item showed a second endothermic signal in the temperature range of 260 – 300 °C, which could be assigned to the boiling of the test item.

For the correction of the boiling temperature to standard pressure the test item was assigned to chemical group 5 (e.g. Benzoic acid). According to appendix 8.2a correction value φ = 5.85 was used for the temperature range from 270 °C to 280 °C.

The lowest measured onset temperature is corrected to the standard pressure to be 277.73 °C and the highest onset temperatureto be 277.87 °C. As the corrected onset temperatures in both tests do not deviate by more than 0.5 K from their mean value of 277.80 °C, this temperature can be used as boiling point. The test item has a boiling point of 277.8 °C.

Applicant's summary and conclusion

Conclusions:

4-Chlorobenzoic acid has a boiling point of 277,8 °C at atmospheric pressure (1013 hPa).

Executive summary:

The test item p-Chlorobenzoic acid has a boiling point of 277,8 °C at standard pressure (1013 hPa) as determined by Differential Scanning Calorimetry according to Regulation (EC) No 440/2008 Method A.2. and OECD Test Guideline 103 (1995).