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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Ongoing
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2022

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 211 (Daphnia magna Reproduction Test)
Version / remarks:
Version: 2012.
Remark: Standard OECD TG 211 but implementing recommendations of OECD Series on Testing and Assessment No. 317: "Guidance document on aquatic and sediment toxicological testing of nanomaterials".
Qualifier:
according to guideline
Guideline:
other: OECD Series on Testing and Assessment No. 317: "Guidance document on aquatic and sediment toxicological testing of nanomaterials"
Version / remarks:
Version: 2021.
Remark: The recommendations of this guidance were implemented when applying the standard OECD 211 test guideline.
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Cerium gadolinium oxide
EC Number:
953-470-2
Molecular formula:
Gd2CeO5
IUPAC Name:
Cerium gadolinium oxide
Test material form:
solid: nanoform

Sampling and analysis

Analytical monitoring:
yes
Details on sampling:
Sampling for analytical monitoring once a week before and after test medium renewal.

Test solutions

Vehicle:
no
Details on test solutions:
The preparation of the stock suspension is based on the recommendations of OECD Series on Testing and Assessment No. 317: "Guidance document on aquatic and sediment toxicological testing of nanomaterials" and on preliminary assays to determine relevant sonication time/amplitude, and concentration.

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
semi-static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
21 d

Test conditions

Details on test conditions:
The test conditions will be further described when the study will be finished and the study report will become available (see in the field "Overall remarks, attachments" for further information).

Results and discussion

Effect concentrations
Key result
Remarks on result:
other: Results not yet available; see in the field "Overall remarks, attachments" for further information.

Applicant's summary and conclusion