Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 410-400-0 | CAS number: 88671-89-0 SYSTHANE TECHNICAL
Endpoint summary
Administrative data
Description of key information
In bobwhite quail, the acute oral LD50 was 510 mg/kg body weight and the NOEL was <316 mg/kg body weight. In short term dietary studies, the 8-day LD50’s for bobwhite quail and mallard duck were >567 and >1550 mg/kg b.w./day, respectively. The NOEC values for quail and mallards were 205 and 806 mg/kg b.w./day for quail and mallard, respectively. In a one-generation reproduction study in bobwhite quail, statistically significant differences in mean day 14 hatchling body weights were noted in the 75 and 180 mg/kg treatment groups. These were not considered to be treatment-related findings, however, because the next highest treatment group was not affected. The reproductive NOEL was 22.5 mg/kg b.w./day. In a one-generation reproduction study in mallard duck, the reproductive NOEL was 24.3 mg/kg b.w./day.
The acute LD50 for earthworms is 250 mg/kg dry soil. Myclobutanil was also shown to not bioaccumulate in earthworms with a calculated bioconcentration factor of 0.46.
Myclobutanil had no effect on carbon mineralization and nitrogen transformation at an application of 0.756 mg/kg dry soil.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
