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Physical & Chemical properties

Boiling point

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boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Test dates: July 24 to August 6, 2015
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
The study was conducted according to an internationally recognised method, and under GLP, but experimental details are missing. The substance is adequately characterised. Therefore validation applies with restrictions.
according to guideline
EU Method A.2 (Boiling Temperature)
GLP compliance:
yes (incl. QA statement)
issued 05 March 2015
Type of method:
differential scanning calorimetry
Specific details on test material used for the study:
- Physical state: Colourless translucent liquid
- Storage condition: Room temperature protected from direct sun light.
Key result
Boiling pt.:
254.6 °C
Atm. press.:
ca. 1 atm

Table 4.3/1: Boiling point – results

Test No.

Start temperature

Heating rate

Onset temperature


70 °C

+10 °C/min



200 °C

+10 °C/min



180 °C

+10 °C/min



200 °C

+10 °C/min



200 °C

+10 °C/min


Mean ± S.D

254.6 ± 0.3 °C

Five successive tests were performed. (*)The last three ones were retained. The validity criteria for repeatability were fulfilled: the standard deviation within the three replicate assessments did not exceed 0.5 °C.Therefore the average value is retained as final result.

Mean onset for boiling occurred at 254.6°C ± 0.3 °C (from assays 3, 4 and 5).

Executive summary:

The boiling point of the test substance was determined under GLP according to EU A2 guideline, using Differential Scanning Calorimetry (DSC) method.

The mean of three consistent determinations was retained.

The boiling temperature of test substance was determined to be 254.6°C, at ca atmospheric pressure.

Description of key information

Experimental boiling point = 254.6°C (atmP not specified).

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
254.6 °C

Additional information

A reliable experimental study, conducted according to a recognized EC method and under GLP, is available.

Despite restrictions due to missing experimental details, it is considered as key study, and the result is retained as key data.