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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 305 B (Bioaccumulation: Semi-static Fish Test)
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
473-730-4
EC Name:
-
Cas Number:
928768-73-4
Molecular formula:
C13H28SO3
IUPAC Name:
1-Octanol reaction products with epichlorhydrin and 2-mercaptoethanol
Test material form:
liquid: viscous
Details on test material:
Expiry Date: July, 31st, 2020
Lot# 2305425
Radiolabelling:
no

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
other: rare minnow (Gobiocypris rarus)
Details on test organisms:
The test adopted Rare minnow (Gobiocypris rarus) (Batch No.: F20180306G) were obtained as fry from a fish supplier of Institute of Hydrobiology, Chinese Academy of Sciences. Their average body length was 3.0 +/- 0.5 cm (ncluding the lenth of their tail). And average body wetweight was 0.2 +/- 0.1 g.

Study design

Route of exposure:
aqueous
Test type:
semi-static
Water / sediment media type:
natural water: freshwater
Total exposure / uptake duration:
28 d
Total depuration duration:
15 d

Test conditions

Hardness:
184.9 mg (CaCO3)/L
Test temperature:
23 +/- 2 °C
pH:
7.35 - 8.00 (test solution during test)
8.17 (dilution water)
Reference substance (positive control):
not specified

Results and discussion

Bioaccumulation factoropen allclose all
Key result
Conc. / dose:
0.1 mg/L
Temp.:
>= 22.7 - <= 23.4 °C
pH:
7.65
Type:
BCF
Value:
15 dimensionless
Basis:
whole body w.w.
Key result
Conc. / dose:
1 mg/L
Temp.:
>= 22.7 - <= 23.4 °C
pH:
7.65
Type:
BCF
Value:
36.7 dimensionless
Basis:
whole body w.w.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
During the test (28 d), U136 in fishes were 1.25 and 30.8 mg/kg, respectively, when exposed to 0.10 mg/L and 1.00 mg/L solution. So the BCFsvalue of the test substance are 15.0 and 36.7, respectively.
Executive summary:

During the test (28 d), U136 in fishes were 1.25 and 30.8 mg/kg, respectively, when exposed to 0.10 mg/L and 1.00 mg/L solution. So the BCFsvalue of the test substance are 15.0 and 36.7, respectively.