Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
adsorption / desorption: screening
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Study period:
2004
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2004
Report date:
2004

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC estimation method
Media:
soil

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
Identity: ucb 22060
Batch: C03425-3176
Purity: > 99%
Appearance: Solid, white powder
Storage: At room temperature (approx. 20°C)
Radiolabelling:
not specified

Study design

Batch equilibrium or other method

Analytical monitoring:
not specified

Results and discussion

Adsorption coefficient
Type:
log Koc
Value:
-0.3

Applicant's summary and conclusion

Conclusions:
In conclusion, the log of the adsorption coefficient (Koc) of ucb 22060 was estimated to be log KOC = -0.3 which is equal to a Kocvalue of 0.5 using the HPLC method. This value indicates that ucb 22060 will not be absorbed by organic carbon in soil and that ucb 22060 is very high mobile.

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