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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2004
Report date:
2004

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 405 (Acute Eye Irritation / Corrosion)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 870.2400 (Acute Eye Irritation)
Deviations:
no
Qualifier:
according to guideline
Guideline:
other:
Deviations:
no

Test material

Constituent 1
Test material form:
solid: particulate/powder

Test animals / tissue source

Species:
rabbit
Strain:
New Zealand White

Results and discussion

In vivo

Resultsopen allclose all
Irritation parameter:
conjunctivae score
Basis:
animal #1
Time point:
other:
Score:
0
Irritation parameter:
conjunctivae score
Basis:
animal #2
Time point:
other:
Score:
2
Irritation parameter:
conjunctivae score
Basis:
animal #3
Time point:
other:
Score:
1
Irritation parameter:
conjunctivae score
Max. score:
2
Remarks on result:
other:
Irritation parameter:
chemosis score
Basis:
animal #1
Time point:
other:
Score:
0
Irritation parameter:
chemosis score
Basis:
animal #2
Time point:
other:
Score:
0
Irritation parameter:
chemosis score
Basis:
animal #3
Time point:
other:
Score:
0
Irritation parameter:
chemosis score
Max. score:
0
Remarks on result:
other:
Irritation parameter:
cornea opacity score
Basis:
animal #1
Time point:
other:
Score:
0
Irritation parameter:
cornea opacity score
Basis:
animal #2
Time point:
other:
Score:
0
Irritation parameter:
cornea opacity score
Basis:
animal #3
Time point:
other:
Score:
0
Irritation parameter:
cornea opacity score
Max. score:
0
Remarks on result:
other:
Irritation parameter:
iris score
Basis:
animal #1
Time point:
other:
Score:
0
Irritation parameter:
iris score
Basis:
animal #2
Time point:
other:
Score:
0
Irritation parameter:
iris score
Basis:
animal #3
Time point:
other:
Score:
0
Irritation parameter:
iris score
Max. score:
0
Remarks on result:
other:

Applicant's summary and conclusion