A mixture of: (9-cis,12-cis)-2-hydroxy-3-(octadeca-9,12-dienoylamino)propyl hexadecanoate; (9-cis)-2-hydroxy-3-(octadeca-9-enoylamino)propylhexadecanoate ethyl hexadecanoate;

Partition coefficient

Administrative data

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Study period:

December 2014

Reliability:

1 (reliable without restriction)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2014

Report date:

2014

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)

Deviations:

no

GLP compliance:

no

Type of method:

HPLC method

Partition coefficient type:

octanol-water

Test material

Reference

Name:

Unnamed

Type:

Constituent

Test material form:

other: whitish scales

Study design

Analytical method:

high-performance liquid chromatography

Results and discussion

Partition coefficient

Key result

Type:

log Pow

Partition coefficient:

6.174

Temp.:

25 °C

pH:

7

Applicant's summary and conclusion

Conclusions:

The chromatogram of the test item gave one peak. With the calibration function log K versus log Pow, the corresponding log Pow was determined with
- mean retention time : 35.577
- log Pow : 6.174

Executive summary:

The partition coeficient of Omega 6 ceramide was conducted according to OECD 117 guideline. The chromatogram of the test item gave one peak. With the calibration function log K versus log Pow, the corresponding log Pow was determined with - mean retention time : 35.577 - log Pow : 6.174