Registration Dossier
Registration Dossier
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EC number: 406-420-4 | CAS number: 69430-40-6 DC 5067
Solubility in organic solvents / fat solubility
Administrative data
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- April 15, 1991
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Report date:
- 1991
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 116 (Fat Solubility of Solid and Liquid Substances)
- Qualifier:
- according to guideline
- Guideline:
- other: EEC guideline (European Economic Community (EEC), EEC Directive 841449 EEC, Annex, part A: Methods for the determination of physico-chemical properties, A.7:"Fat solubility", EEC Publication No.L251, September 1984
- GLP compliance:
- yes
Test material
- Reference substance name:
- α-trimethylsilanyl-ω-trimethylsiloxypoly[oxy(methyl-3-(2-(2-methoxypropoxy)propoxy)propylsilanediyl]-co-oxy(dimethylsilane))
- EC Number:
- 406-420-4
- EC Name:
- α-trimethylsilanyl-ω-trimethylsiloxypoly[oxy(methyl-3-(2-(2-methoxypropoxy)propoxy)propylsilanediyl]-co-oxy(dimethylsilane))
- Cas Number:
- 69430-40-6
- Molecular formula:
- Unspecified example: C18.3H46.8O5.8Si4.1
- IUPAC Name:
- 2,2,4,4,6,12,15-heptamethyl-6-[(trimethylsilyl)oxy]-3,5,10,13,16-pentaoxa-2,4,6-trisilaheptadecane
- Details on test material:
- - Name of test material (as cited in study report): DC 5067
- Substance type: Reaction mass (mixture)
- Physical state: Liquid
- Analytical purity: > 99%
- Lot/batch No.: AB 090122
- Expiration date of the lot/batch: December 1, 1991
- Stability under test conditions: Stable
- Storage condition of test material: In the original container at room temperature in the dark
- Other:
Constituent 1
Results and discussion
Solubility in organic solvents / fat solubility
- Medium:
- standard fat
- Remarks:
- HB 307
- Solubility:
- >= 0.01 - <= 100 vol%
- Temp.:
- 37 °C
- Test substance stable:
- yes
Applicant's summary and conclusion
- Conclusions:
- DC 5067 was determined to be miscible with standard fat HB 307.
- Executive summary:
Because.in the preliminary test the test substance appeared to be miscible with standard fat HB 307 in a 1:l ratio (v/v), the main study was not performed. Alternatively, the fat miscibility at different ratio's was tested. The test substance DC 5067 was determined to be miscible with standard fat HB 307. At different ratios "test substance/standard fat (vlv)", ranging between 100 and 0.01, clear, light brown mixtures were observed. The temperature of measurement was 37.0 +- 0.5°C.
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