Hexaphenoxycyclotriphosphazene

Bioaccumulation: aquatic / sediment

Link to relevant study record(s)

Reference

Endpoint:

bioaccumulation in aquatic species: fish

Type of information:

experimental study

Adequacy of study:

key study

Study period:

27 Feb to 6 May 2004

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: - Study generated according to generally valid and/or internationally accepted testing guidelines - Performed according to GLP - Test parameters based on specific testing guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 305 (Bioconcentration: Flow-through Fish Test)

Deviations:

no

Principles of method if other than guideline:

N/A

GLP compliance:

yes (incl. QA statement)

Specific details on test material used for the study:

Details on properties of test surrogate or analogue material (migrated information):
See attached report

Radiolabelling:

no

Details on sampling:

See attached report

Vehicle:

yes

Details on preparation of test solutions, spiked fish food or sediment:

See attached report

Test organisms (species):

Cyprinus carpio

Details on test organisms:

See attached reprot

Route of exposure:

aqueous

Test type:

flow-through

Water / sediment media type:

natural water: freshwater

Total exposure / uptake duration:

28 d

Hardness:

87 mg/L

Test temperature:

25 °C

pH:

7.7-7.9

Dissolved oxygen:

8.1 mg/L

TOC:

N/A

Salinity:

N/A

Details on test conditions:

See study reprot

Nominal and measured concentrations:

0.1 and 0.01 mg/L

Reference substance (positive control):

no

Details on estimation of bioconcentration:

See study report

Lipid content:

3.8 %

Time point:

start of exposure

Lipid content:

3.5 %

Time point:

end of exposure

Type:

BCF

Value:

ca. 12 dimensionless

Basis:

whole body w.w.

Time of plateau:

28 d

Calculation basis:

steady state

Remarks on result:

other: Conc.in environment / dose:0.1

Details on kinetic parameters:

See Report

Metabolites:

N/A

Results with reference substance (positive control):

N/A

Details on results:

See attached report

Reported statistics:

None reported

Validity criteria fulfilled:

yes

Conclusions:

BCF was determined to be 12.04

Description of key information

BCF value for FP-100 has been determined to be 12.04

Key value for chemical safety assessment

BCF (aquatic species):

12.04 dimensionless

Additional information

Previous assessment by HSE had questioned the validity of this test and hence recommended to classify FP-100 as bioaccumulative. The study has been reviewed by an ecotoxicologist and his comments are in the document attached below. His evalaution confirms that the study is valid and that the substance is not bioaccumulative.