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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

Measured data: monoethylene glycol, 7 day NOEC in Ceriodaphnia: 8590mg/l.  

QSAR data: Chv values: 767, 2100, 78000mg/l

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
8 590 mg/L

Additional information

There is chronic toxicity data on one of the three constituents of this substance. This substance (MEG) is likely to represent the most toxic of the three components based on the acute toxicity information available. QSAR data also suggests that the toxicity decreases with increasing molecular weight and therefore that monoethylene glycol (MEG) is likely to be the most toxic species. The QSAR does not include a specific class covering acetate salts but predicts that the same neutral organics class can be used as an alternative. The QSAR predicts that sodium acetate will be less toxic that MEG, which confirms that the reliable measured data from MEG can be used as a conservative alternative to predict the overall toxicity of the substance. The experimental data on MEG is a 7 day study in Ceriodaphnia, which can be considered a reliable chronic study. Overall, it is clear that all of the components present very low chronic toxicity. The key parameter is based on the available data for MEG.