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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1930
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Mice were dosed with up to 1000 mg/kg with the Target Substance and all survived. Although this study is not a guideline study, there is sufficient weight of evidence to conclude that the material is of low acute oral toxicity.

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
1930

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
please refer to the executive summary
GLP compliance:
no
Test type:
standard acute method
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3-methoxybutyl acetate
EC Number:
224-644-9
EC Name:
3-methoxybutyl acetate
Cas Number:
4435-53-4
Molecular formula:
C7H14O3
IUPAC Name:
3-methoxybutyl acetate
Constituent 2
Reference substance name:
Butoxyl
IUPAC Name:
Butoxyl

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Doses:
100 mg/kg bw
500 mg/kg bw
1000 mg/kg bw
6 x once /day 100mg/kg
No. of animals per sex per dose:
two per dose
Control animals:
not specified

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 1 000 mg/kg bw
Mortality:
No mortality observed
Other findings:
Animals remained healthy

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
After oral application of up 1000 mg/kg bw, no mortality occured.
Executive summary:

Test material was administered as single dose at levels: 100 mg/kg bw; 500 mg/kg bw and 1000 mg/kg bw. No effects were observed at the treatment doses.

LD 50 > 1000 mg/kg bw.