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EC number: 932-179-4 | CAS number: -
Tables and figures of the Preliminary Irritation study and Main study have been included in the attached document "LLNA tables and figures".
Results Preliminary irritation study:
No irritation and no signs of systemic toxicity were observed in any of the animals examined.
Brown remnants of the test substance were present at 100% but did not hamper scoring of the ears. Based on these results, the highest test substance concentration selected for the main study was a 100% concentration.
Other results - main study:
No irritation of the ears was observed in any of the animals examined. Brown remnants of the test substance were present at 100% but did not hamper scoring of the ears.
Most auricular lymph nodes at 100% were enlarged in size. The auricular lymph nodes at 25 and 50% were considered normal in size. No macroscopic abnormalities of the surrounding area were noted in any of the animals.
Body weights and body weight gain of experimental animals remained in the same range as controls over the study period. The slight body weight loss, noted in some animals, was considered not toxicologically significant.
No mortality occurred and no symptoms of systemic toxicity were observed in the animals of the main study.
An EC3 value (the estimated test substance concentration that will give a SI =3) of 57.4% was calculated.
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