Registration Dossier
Registration Dossier
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EC number: 209-952-3 | CAS number: 598-78-7
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
The IUCLID 4 dataset reports three results regarding genetic toxicity in vitro.
The three tests are summarised in the table below :-
| Test Method | Test Sysyem | Metabolic Activity | Result | GLP | |
| Test 1 (7.6,001) | OECD 471 (Ames) | S. typhimurium TA 1535, TA 1537, TA 98 and TA 100 | With and without | Negative | Yes |
| Test 2 (7.6, 002) | Ames | Not indicated | Not indicated | Negative | No Data |
| Test 3 (7.6, 003) | SOS-Chromotest | Escherichia coli | Without | Negative | No Data |
All three taken together contribute to the weight of evidence that 2 -chloropropionic acid is considered to be non-mutagenic.
Short description of key information:
Three study results are presented in the IUCLID 4 dossier and all report a negative result in the in vitro genetic toxicity studies, therefore no classification is required.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
The conclusions from the three studies confirm that 2 -chloropropionic acid is considered to be non-mutagenic and therefore does nor warrant classification.
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