Registration Dossier
Registration Dossier
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EC number: 212-855-9 | CAS number: 873-94-9
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.18 mg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 1.8 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.018 mg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 28.62 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.96 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.096 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.39 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
As a result of the hazard assessment it can be concluded that 3,3,5 -trimethylcyclohexanone does not meet the criteria for classification as dangerous or to be considered as PBT/vPvB.
However, a comparison of the available data (environmental effects data) for 3,3,5 -trimethylcyclohexanone with the criteria for ecotoxicological properties specified in B.8.3.2 reveals the need to perform an exposure assessment for environmental protection target(s) and subsequent risk characterization, based on the following identified hazards:
Criteria according to B.8.3.2 |
Data for 3,3,5-Trimethylcyclohexanone (CAS: 873-94-9) |
Criteria fulfilled? |
Very low potential to bioaccumulate (BCF <10 or log Kow < 2.0) |
Log Kow: 2.6 (AQura 2010). No BCF available. |
no |
Readily biodegradable |
Not readily biodegradable (OECD 301D), 59% in 28 days. |
no |
Aquatic toxicity: |
|
|
E(L)C50 > 1000 mg/L or > water solubility or no adverse effects at 100 mg/L and validated QSAR data > 1000 mg/L |
Water solubility: 3200 mg/L EC50 (daphnia): 180 mg/L EC50 (algae): >100 mg/L LC50 (fish): > 100 mg/L LOEC (fish) = 100 mg/L (sublethal effects) |
no |
NOEC or EC10 > 10 mg/L |
No chronic data available. |
|
No adverse effects on terrestrial organisms |
No exposure to soil possible due to use of the substance as monomer in closed systems. |
|
No endocrine activity |
No data available. |
|
Conclusion on classification
3,3,5-Trimethylcyclohexanone is of low toxicity to the environment, and does not need to be classified for ecotoxicity.
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