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EC number: 220-260-0 | CAS number: 2691-41-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
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- Nanomaterial surface chemistry
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- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
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- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The effects of HMX to fish was assessed under static conditions in two freshwater acute toxicity studies. The 96h LC50 of the test substance to Pimephales promelas is > 15 mg/L (nominal concentration) (U.S. Army Medical Research and Development Command, 1984).The 96h-LC50 of the test substance to Lepomis macrochirus, Salmo gairdneri, Ictalurus punctatus and Pimephales promelas was greater than 32 mg/L (nominal concentration) (EG & G Bionomics, 1978).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 15 mg/L
Additional information
The LC50 values are based on nominal concentrations. In the study by the U.S. Army Medical Research and Development Command, (1984), undissolved chemical was present on the bottom of the test vessels. These studies were performed at the limit of solubility of HMX (4.46 mg/L at 25C in pure water). A study was conducted using vertebrate reconstituted water at concentrations of 10.0, 5.0 and 2.5 rng/L of HMX. No solvents were utilised. Solutions were analysed immediately, after 24 hours, 48 hours and 1 week of continuous stirring at 25C. These results indicated that the HMX was most completely solubilised between 48 hours and 1 week of mixing and that the expected concentration at saturation should be ca. 2.8 mg/L (see Table 1).
Table 1: Solubility of Test substance in Vertebrate Dilution Water |
|||||
Sample Concentration |
Analytical Results (mg/L) |
Remarks |
|||
0 hoursa |
24 hoursa |
48 hoursa |
1 weeka |
||
2.5 mg/L vert. |
0.09 0.11 0.12 mean=0.11 |
0.58 0.59 0.57 mean=0.57 |
1.3 1.3 mean=1.3 |
2.5 2.5 mean=2.5 |
@ 48h, tepm. 27° also remained warm |
5.0 mg/L vert. |
0.16 0.14 0.20 mean=0.17 |
2.8 2.7 2.8 mean=2.8 |
4.0 4.1 mean=4.0 |
4.2 4.2 mean=4.2 |
@ 48h, tepm. 25.5° |
10 mg/L vert. |
0.23 0.24 0.23 mean=0.23 |
1.1 1.2 1.2 mean=1.2 |
1.8 1.8 mean=1.8 |
2.9 2.9 mean=2.9 |
@ 48h, tepm. 26° |
aRepresents amount of time mixed prior to analysis.
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