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EC number: 213-139-9 | CAS number: 926-63-6
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Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Dimethyl(propyl)amine is with high propability not harmful to aquatic invertebrates.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
In a GLP-study conducted with Daphnia magna according to OECD guideline 202, the acute toxicity of the test substance on aquatic invertebrates was studied (BASF, 1999, report no. 99/0066/50/1). After 48 hours of exposure an EC50 value based on mobility of the test animals was determined to be 28.7 mg/L. However, this effect value was derived from samples in which the pH values were not adjusted. In test solutions containing 25 mg/L or more test substance the pH ranged from 9.3 to 10.1 at test initiation. In parallel test solutions of 25, 50 and 100 mg/L, the pH of the dilution water was adjusted to that of the medium. Only a single daphnid was immobile after 48 hours exposure to 100 mg/L neutralized test item concentration and consequently the EC50 after 48 hours is > 100 mg/L after pH-adjustment.
For the risk assessment the effect data for the neutralized test medium should be used since the quantities of the substance that would be found in natural waters are not likely to affect the pH to a relevant extent. It is likely that the L(E)C-values from the tests without neutralization overestimate the potential toxicity of these matrices.
Therefore it may be proposed that dimethyl(propyl)amine is considered to be with high propability acutely not harmful to aquatic invertebrates.
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