Registration Dossier
Registration Dossier
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EC number: 252-043-1 | CAS number: 34454-97-2
Endpoint summary
Administrative data
Description of key information
Additional information
C4 sulfonamido alcohol underwent primary biodegradation in an inherent biodegradability test, forming C4 glycine acid as a stable product, with ca. 97% conversion to the glycine acid within 28 days. Accordingly, toxicity of both C4 sulfonamido alcohol and C4 glycine acid was examined. C4 sulfonamido alcohol showed considerably more aquatic toxicity than C4 glycine acid, with the marine invertebrate Mysidopsis bahia being the most sensitive species tested. While a water solubility limit of the glycine acid is not available, test solutions were, in most cases, clear and colorless throughout the test at a nominal concentration of 100 mg/L.
Test organism |
Result for C4 sulfonamido alcohol |
Result for C4 glycine acid |
Fish |
|
|
Pimephales promelas |
OPPTS 850.1075 and OECD 203: 96-h LC50, 25 mg/L |
OECD 203: 96-h LC50, >100 mg/L (no effects observed)* |
Invertebrate |
|
|
Daphnia magna (freshwater) |
OPPTS 850.1010 and OECD 202: 48-h EC50, 38 mg/L |
OECD202: 48-h EC50, >100 mg/L (no effects observed) |
Mysidopsis bahia (estuarine) |
OPPTS 850.1035: 96-h LC50, 4.4 mg/L |
OPPTS 850.1035: 96-h LC50, >100 mg/L (no effects observed) |
Algae |
|
|
Pseudokirchneriella subcapitata |
OPPTS 850.5400 and OECD 201: 72-h EC50, 79 mg/L (growth rate) 72-h NOEC, 21 mg/L (growth rate) |
OECD 201: 72-h EC50, invalid due to acidification of medium, no biologically significant effects up to 50 mg/L (nominal) |
Microorganisms |
|
|
Activated sludge (respiration) |
OECD 209: >1000 mg/L |
OECD 209 >1000 mg/L |
*Test solution cloudy throughout study. All other studies had clear test solutions throughout.
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