Registration Dossier
Registration Dossier
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EC number: 202-784-1 | CAS number: 99-75-2
Epidemiological data
Administrative data
- Endpoint:
- epidemiological data
- Type of information:
- other:
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Study period:
- 1962
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Secondary source
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- IUCLID Dataset Substance ID: 99-75-2
- Author:
- IUCLID
- Year:
- 2 000
- Bibliographic source:
- http://esis.jrc.ec.europa.eu/ with reference to Montefibre S.p.A
- Report date:
- 2000
- Reference Type:
- secondary source
- Title:
- Fragrance raw materials monographs. Methyl p-toluate
- Author:
- Opdyke DLJ
- Year:
- 1 979
- Bibliographic source:
- Food and Cosmetics Toxicology, Vol. 17 Suppl. 183-184
- Report date:
- 1979
Materials and methods
- Study type:
- other: workplace experience, not further specified
- Endpoint addressed:
- repeated dose toxicity: inhalation
- Principles of method if other than guideline:
- Occupational health study
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Methyl p-toluate
- EC Number:
- 202-784-1
- EC Name:
- Methyl p-toluate
- Cas Number:
- 99-75-2
- Molecular formula:
- C9H10O2
- IUPAC Name:
- methyl 4-methylbenzoate
- Test material form:
- other: vapour
- Details on test material:
- no data
Constituent 1
Method
- Details on study design:
- no data
- Exposure assessment:
- not specified
Results and discussion
- Results:
- Workers exposed to methyl-p-toluate, among other substances, were reported to have shown moderate leucocytosis at the extense of neutrophils in several cases
- Confounding factors:
- other, unknown substances
Applicant's summary and conclusion
- Conclusions:
- No definite conclusions can be drawn from this study due to the presence of other, unknown substances at the workplace.
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