Registration Dossier
Registration Dossier
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EC number: 221-660-8 | CAS number: 3179-76-8
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Biodegradation in water: screening tests: No significant biodegradation is expected for the silanol hydrolysis product, based on read-across from a structurally-related substance.
Key value for chemical safety assessment
Additional information
There are no reliable ready biodegradation data available for 3-(diethoxymethylsilyl)propylamine, therefore good quality data for the structurally-related substance, 3-aminopropyltriethoxysilane (CAS 919-30-2), have been read across. Both substances hydrolyse to structurally-related hydrolysis products,
3-(dihydroxymethylsilyl)propylamine
and3-aminopropylsilanetriol
, respectively. The other hydrolysis product in both cases is ethanol, which is readily biodegradable.Both
3-(diethoxymethylsilyl)propylamine
and3-aminopropyltriethoxysilane
are within an analogue group of substances within which, in general, there is no evidence of any significant biodegradation once biodegradation of alkoxy/acetoxy groups has been taken into account.It is therefore considered valid to read-across the results for
3-aminopropyltriethoxysilane
to fill the data gap for the registered substance. Additional information is given in a supporting report ( PFA, 2013f) attached in Section 13 of the IUCLID 5 dossier.3 -Aminopropyltriethoxysilane attained
67% biodegradation in 28d. This biodegradation is attributable to the biodegradation of the ethanol hydrolysis product, which is readily biodegradable.No significant biodegradation is expected for the silanol hydrolysis product. A slightly lower degradation % would be expected for3-(diethoxymethylsilyl)propylamine, as a lower proportion of carbons in the structure are associated with alkoxy groups. However, the conclusion of nosignificant biodegradation expected for the silanol hydrolysis product is read-across.The study is considered to be reliability 1 (reliable without restrictions); the read across of the result is considered to be reliability 2 (reliable with restrictions).
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