Registration Dossier
Registration Dossier
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EC number: 221-660-8 | CAS number: 3179-76-8
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
(48-h) EC50: 331 mg/l mobility Daphnia magna (read-across from 919-30-2), reliability 2
(48-h) LC50: 580 mg/l mortality Acartia tonsa (read-across from 919-30-2), reliability 2
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 331 mg/L
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 580 mg/L
Additional information
There are no reliable data for the substance. However a 48-hour EC50 of 331 mg/l and NOEC of 94 mg/l have been determined for the effects of the structurally related substance, 3-aminopropyltriethoxysilane (CAS 919-30-2) on mobility of Daphnia magna. A 48-hour LC50 of 580 mg/L and NOEC of 336 mg/L have also been determined for the effects of the same read-across substance on mortality of the marine invertebrate Acartia tonsa. The test substance is susceptible to hydrolysis and it is therefore likely that the test organisms were exposed to the hydrolysis products of the substance.
The studies were conducted according to appropriate OECD and ISO test guidelines, and in compliance with GLP, and were considered to be reliability 1 (reliable without restrictions). Read across to the registered substance is considered scientifically justified; the read across is considered to be reliability 2.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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