Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low concentrations.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
1 000 mg/L

Additional information

Two experimental studies for the toxicity to microorganisms of 1-ethylpiperazine (CAS 5308-25-8) are available.

An OECD 209 respiration inhibition tests was performed with activated sludge from municipal sources. The 30-min EC20 was determined to be > 1000 mg/L. The 30 -min NOEC was 1000 mg/L (nominal, BASF AG, 1990, rep. no.: 01.0387/88).

In a second study, regarding growth inhibition of Pseudomonas putida, the 17-h EC10 was 141.4 mg/L (nominal, not pH-adjusted). The study was conducted according to the German Industrial Standard DIN 38412, part 8 (BASF AG, 1988, rep. no.: 9/0843/88).


Based on the available experimental data the substance is not anticipated to inhibit the degradation activity of activated sludge when introduced in appropriately low concentrations.