Registration Dossier

Ecotoxicological information

Toxicity to microorganisms

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Toxicity to microorganisms: 3-hour ASRI EC50 463 mg/l and EC10 32.6 mg/l, based on read-across from an analogous substance.

Key value for chemical safety assessment

Additional information

There are no microorganism toxicity data available for

3 -(triethoxysilyl)propanethiol

, therefore good quality data for the analogous substance

3 -(trimethoxysilyl)propanethiol

(CAS 4420 -74 -0), have been read across. Both substances share the same silanol hydrolysis product,

3 -(trihydroxysilyl)propanethiol

; the other hydrolysis products being ethanol and methanol, respectively, both of which are not toxic to sewage treatment plant microorganisms.

3 -(Triethoxysilyl)propanethiol


3 -(trimethoxysilyl)propanethiol

are within an analogue group of substances that exhibit evidence of some toxicity to microorganisms

It is therefore considered valid to read-across the results for

3 -(trimethoxysilyl)propanethiol

to fill the data gap for the registered substance. Additional information is given in a supporting report (PFA, 2013n) attached in Section 13 of the IUCLID 5 dossier.

A 3 hour ASRI EC50 value of 463 mg/l (nominal) and EC10 value of 32.6 mg/l (nominal) were determined for

3 -(trimethoxysilyl)propanethiol.