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EC number: 907-706-6 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Biodegradation in water
The Ready Biodegradability of test chemical was determined by the Manometric Respirometry Test according to the OECD Guidelines for Testing of Chemicals, Method No. 301 F. The test chemical undergoes 71% biodegradation after 28 days in the test conditions. The 10 -day window criterion is also fulfilled (16% biodegradation on day 4 and 65% on day 14). The curves obtained with the reference substance alone and with test chemical + reference substance show no toxic effect to the micro-organisms at the test concentration (100 mg/l). Thus, the test chemical should be regarded as readily biodegradable according to this test.
Biodegradation in water and sediment
Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound. The Test chemical If released in to the environment, 15.4 % of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of the chemical in water is estimated to be 37.5 days (900 hrs). The half-life (37.5days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is low whereas the half-life period of Test chemical in sediment is estimated to be 337.5 days (8100 hrs). However, as the percentage release of test chemical into sediment is less than 1 %( i.e., reported as 0.567 %) indicates that test chemical is not persistent in sediments.
Biodegradation in soil
The half-life period of Test chemical in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 84 % of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemical in soil is estimated to be 75 days (1800 hrs). Based on this half-life value of test chemical, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low.
Additional information
Biodegradation in water
Various experimental studieshas been investigated for the test chemicalfor reviewing the biodegradation endpointwhich have beensummarized as below;
The Ready Biodegradability of test chemical was determined by the Manometric Respirometry Test according to the OECD Guidelines for Testing of Chemicals, Method No. 301 F. The test chemical undergoes 71% biodegradation after 28 days in the test conditions. The 10 -day window criterion is also fulfilled (16% biodegradation on day 4 and 65% on day 14). The curves obtained with the reference substance alone and with test chemical + reference substance show no toxic effect to the micro-organisms at the test concentration (100 mg/l). Thus, the test chemical should be regarded as readily biodegradable according to this test.
The another Manometric Respirometry Test was conducted for test chemical to assess its percent degradation as per the OECD Guidelines for Testing of Chemicals, Method No. 301 F. The Test chemical undergoes 60% biodegradation after 28 days (65% after 36 days) in the test conditions. Biodegradation exceeds 10% on day 8 and reaches only 52% at the end of the 10-day window (days 8 to 18).The curves obtained with the reference substance alone and with Test chemical + reference substance show no toxic effect of Test chemical to the micro-organisms at the test concentration (100 mg/I).Thus, Test chemical should be regarded as readily biodegradable according to this test.
The above results were supported by Biodegradation study conducted according to OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test) for 28 days for evaluating the percentage biodegradability of test substance. The percentage degradation of the test substance was determined to be 75.4% by using CO2 evolution parameter. Thus, based on percentage degradation of test chemical, the chemical was considered to be readily biodegradable in nature.
By considering results of all the studies mentioned above it can be concluded that the test chemical can be expected to be readily biodegradable in nature.
Biodegradation in water and sediment
The predicted data of test chemical for Biodegradation in water and sediment endpointhave beensummarized as below;
Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound. The Test chemical If released in to the environment, 15.4 % of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of the chemical in water is estimated to be 37.5 days (900 hrs). The half-life (37.5days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is low whereas the half-life period of Test chemical in sediment is estimated to be 337.5 days (8100 hrs). However, as the percentage release of test chemical into sediment is less than 1 %( i.e., reported as 0.567 %) indicates that test chemical is not persistent in sediments.
According to Estimation Programs Interface (EPI Suite, 2017) prediction model, the test compound If released in to the environment, 14% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of test substance in water is estimated to be 37.5 days (900 hrs). The half-life (37.5 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of test chemical in sediment is estimated to be 337.5 days (8100 hrs). However, as the percentage release of test chemical into the sediment is less than 1% (i.e, reported as 0.515%), indicates that the test chemical is not persistent in sediment.
Based on the available data,it can be concluded that the testchemical is not persistent in water and sediment.
Biodegradation in soil
The predicted data of test chemical for Biodegradation in soil endpointhave been summarized as below;
The half-life period of Test chemical in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 84 % of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemical in soil is estimated to be 75 days (1800 hrs). Based on this half-life value of test chemical, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low.
According to Estimation Programs Interface (EPI Suite, Level III Fugacity; 2017) prediction model, If released into the environment, 85.5% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemical in soil is estimated to be 75 days (1800 hrs). Based on this half-life value of test chemical, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low.
Based on the available data, it can be concluded that the testchemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low.
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