Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

The test material is a polar mixture of a chromium-complex-sulfonic acid salts. Due to the good solubility in water at least partial bioavailability is expected after oral exposure. Based on the polar nature of the molecules a significant absorption through skin as well as a bio-accumulation potential is not suspected. 

Key value for chemical safety assessment

Bioaccumulation potential:
no bioaccumulation potential

Additional information

Acid Brown 425 is a dye for leather. The material is a 2 to 1 complex of chromium 3+ and the products of an azo-coupling reaction of resorcinol with amino-toluene sulfonic acid and anthranilic acid. The material is a mixture of different sulfonic acid salts with highly polar characters.

Absorption: Acid Brown 425 is easily soluble in water. The material is expected to be readily bio-available at the portal of entry and at least partly systemically after oral exposure. Little bio-availability is expected after dermal exposure due to the polar nature of the dye.

Distribution: Due to the good solubility of the dye in water the dye molecules are expected to be distributed throughout the organism. Accumulation in fatty tissue, however, is not expected based on the very polar sulfonic acid moieties in the molecules.

Metabolism: Although the dye may partially become bio-available. Significant metabolism is considered unlikely.

Excretion: As Acid Brown 425 is easily soluble in water the dye is expected to be excreted via the kidney. If applied orally part of the material will be eliminated via the feces.