Registration Dossier

Diss Factsheets

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The octanol/water partition coefficient of a complex reaction product was experimentally measured in accordance with OECD testing guideline 117 and GLP requirements. 93.5% of the components of this UVCB have Log Pow ranged from 3.66 to 4.16.

Key value for chemical safety assessment

Log Kow (Log Pow):
4.16

Additional information

To appraise the octanol/water partition coefficient of a complex reaction product (Ethoxylated bisphenol A diacrylate), this endpoint was experimentally measured in accordance with OECD testing guideline 117 and GLP requirements

A range of octanol/water partition coefficient values at pH 6.44 was obtained: <2.45 to 4.16. 93.5% of the components of this UVCB have Log Pow ranged from 3.66 to 4.16.

The chromatogram obtained by HPLC showed four peaks with three representing each between 12.2% and 42.2% of the total area under the curve and together 93.5% of all the UVCB. The other peak covered then less than 10% of the total area under the curve. Therefore, these three peaks representing the most abundant components of this complex reaction product (>>10%), the highest log value (4.16) in this range was used for chemical safety assessment (CSA). The highest value was considered as a worst-case value, increase of n-octanol/water partition coefficient value leading to a significant increase of Predicted Environmental Concentration in sediments and soil.

Categories Display