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EC number: 290-836-4 | CAS number: 90268-36-3
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
21-day EC10: 1.1 mg/L
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1.1 mg/L
Additional information
In the Klimisch 1 GLP study from Eckenstein (2015) the chronic toxicity of Sulfosuccinic (FA C12-18)E, 2Na on Daphnia magna was determined in an 21 day semi-static test according to OECD 211. The test was performed with concentrations of 0.1375, 0.275, 0.55, 1.1, and 2.2 mg Sulfosuccinic (FA C12-18)E, 2Na /L and a blank control. Ten replicates with 1 Daphnia each were set up. After 21 days 0, 0, 0, 0, 10, 60 and 100% mortality was observed in the control and at nominal test concentrations of 0.1375, 0.275, 0.55, 1.1, and 2.2 mg Sulfosuccinic (FA C12-18)E, 2Na /L, respectively.
The reproduction per parent daphina was 124.6 (10), 145.6 (10), 126.9 (10), 131.7 (10), 127.0 (10), and 98.6 (10) living offspring per parental animal (number of parental daphinds used to calculate the mean are given in brackets) in the control and 0.1375, 0.275, 0.55, 1.1 and 2.2 mg/L, respectively
In the biologically relevant dose groups, the measured test item concentrations in the freshly prepared test media of the nominal concentrations of 0.55 to 2.2 mg/L were between 89 and 112% of the nominal values at the start of the test medium renewal periods. In the aged test media samples without food, the measured concentrations as % nominal were between 83 and 104%. Therefore, the biological results were based on nominal concentrations.
The EC10 for mortality is 1.1 mg/L, the EC10 for reproduction is 1.6 mg/L. Length was not affected. For the risk assessment, the more conservative EC10, i.e., the EC10 for mortality was used.
The result is considered relevant and reliable for the risk assessment.
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