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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
GLP compliance:
yes (incl. QA statement)
Type of method:
determination of fibre length and diameter distributions
Type of distribution:
volumetric distribution
Key result
Percentile:
D50
Mean:
> 10 - < 100 µm
Remarks on result:
other: No source field for Stan dard deviation.
No.:
#1
Size:
< 100 µm
Distribution:
95.8 %
No.:
#2
Size:
< 10 µm
Distribution:
0.505 %
No.:
#3
Size:
< 5.5 µm
Distribution:
0.17 %
Conclusions:
The inhalable fraction (smaller than 100 µm) is 95.8 %, the thoracic fraction (smaller than 10 µm) is 0.505 %, and respirable fraction (smaller than 5.5 µm) is 0.17 %. Thus, the mass median diameter is between 10 and 100 µm.
Executive summary:

The inhalable fraction (smaller than 100 µm) is 95.8 %, the thoracic fraction (smaller than 10 µm) is 0.505 %, and respirable fraction (smaller than 5.5 µm) is 0.17 %. Thus, the mass median diameter is between 10 and 100 µm.

Description of key information

The inhalable fraction (smaller than 100 µm) is 95.8 %, the thoracic fraction (smaller than 10 µm) is 0.505 %, and respirable fraction (smaller than 5.5 µm) is 0.17 %. Thus, the mass median diameter is between 10 and 100 µm.

 

Additional information

Although the inhalable fraction (smaller than 100 µm) is 95.8 %, the thoracic fraction (smaller than 10 µm) is 0.505 %, and the respirable fraction (smaller than 5.5 µm) is only 0.17 %. Thus, the substance may become inhaled but hardly reaches the lower respiratory tract and the inhalative pathway is not of concern. The mass median diameter is between 10 and 100 µm.